Hepatoprotective Activity of Portulaca quadrifida Linn against CCl4 Induced Hepatotoxicity in Rats
نویسندگان
چکیده
Hepatoprotective activity of the ethanolic extract of the shade dried aerial parts of Portulaca quadrifida Linn. was studied in wister rats using the CCl4 induced hepatotoxicity. The activity was evaluated by using biochemical parameters such as serum aspartate amino transferase (AST), alanine amino transferase (ALT), alkaline phosphatase (ALP), total bilirubin and gamma glutamate transpeptidase (GGTP). The extract exhibited significant hepatoprotective activity at 200 mg/kg, p.o. body weight, which was comparable to the control and activity exhibited by the reference standard Silymarin in carbon tetrachloride induced hepatotoxicity model.
منابع مشابه
RESEARCH AND REVIEWS: JOURNAL OF PHARMACOLOGY AND TOXICOLOGICAL STUDIES Effect of Portulaca quadrifida Linn on Mercury-Induced Hepatotoxicity In Swiss Albino Mice
Portulaca quadrifida Linn. has been evaluated for its hepatoprotective activity in Swiss albino mice using the mercury induced hepatotoxicity. The ethanolic extract showed remarkable activity against mercury-induced hepatotoxicity as judged from biochemical parameters such as serum aspartate amino transferase (AST), alanine amino transferase (ALT), alkaline phosphatase (ALP) and levels of lipid...
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